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Anti-Mouse RARRES2 Polyclonal Antibody (MV607014)

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Overview
Catalog No.MV607014
Description
Anti-Mouse RARRES2 Polyclonal Antibody (MV607014) is a rabbit polyclonal antibody detecting Rarres2. Suitable for Mouse.
Species reactivityMouse
ApplicationsELISA, IHC, WB
Host speciesRabbit
IsotypeIgG
Clonality Polyclonal
Immunogen E. coli - derived recombinant Mouse RARRES2 (Ser25-Gly141).
Target Chemerin, Rarres2, Retinoic acid receptor responder protein 2
Endotoxin level Please contact with the lab for this information.
Purification Purified by antigen affinity column.
Accession Q9DD06
Form Liquid
Storage buffer 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Product Usage Information
Application Dilution
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Background

Retinoic acid receptor responder protein 2 (RARRES2) is a ~18 kDa protein. Adipocyte-secreted protein (adipokine) that regulates adipogenesis, metabolism and inflammation through activation of the chemokine-like receptor 1 (CMKLR1). Also acts as a ligand for CMKLR2. Can also bind to C-C chemokine receptor-like 2 (CCRL2), but with a lower affinity than it does to CMKLR1 or CMKLR2. Positively regulates adipocyte differentiation, modulates the expression of adipocyte genes involved in lipid and glucose metabolism and might play a role in angiogenesis, a process essential for the expansion of white adipose tissue. Also acts as a pro-inflammatory adipokine, causing an increase in secretion of pro-inflammatory and prodiabetic adipokines, which further impair adipose tissue metabolic function and have negative systemic effects including impaired insulin sensitivity, altered glucose and lipid metabolism, and a decrease in vascular function in other tissues.

Note For research use only
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Anti-Mouse RARRES2 Polyclonal Antibody

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