

| Catalog No. | MY185013 | ||||
|---|---|---|---|---|---|
| Species reactivity | Mouse, Rat | ||||
| Applications | Blocking, ELISA, SPR | ||||
| Host species | Human | ||||
| Isotype | IgG1, kappa | ||||
| Clone ID | SAA0768 | ||||
| Clonality | Monoclonal | ||||
| Target | PLANH1, Endothelial plasminogen activator inhibitor, SERPINE1, Plasminogen activator inhibitor 1, PAI1, PAI, PAI-1, Serpin E1 | ||||
| Endotoxin level | Please contact with the lab for this information. | ||||
| Purity | >95% as determined by SDS-PAGE. | ||||
| Purification | Protein A/G purified from cell culture supernatant. | ||||
| Accession | P22777 | ||||
| RRID | Anti-Mouse SERPINE1/PAI-1 Antibody (SAA0768) (abinScience Cat# MY185013, RRID:AB_3725639) |
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| Form | Liquid | ||||
| Storage buffer | 0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| Product Usage Information |
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| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. | ||||
| Background | Plasminogen activator inhibitor 1 (SERPINE1/PAI-1) is a ~45 kDa protein. Serine protease inhibitor. Inhibits TMPRSS7. Is a primary inhibitor of tissue-type plasminogen activator (PLAT) and urokinase-type plasminogen activator (PLAU). As PLAT inhibitor, it is required for fibrinolysis down-regulation and is responsible for the controlled degradation of blood clots. As PLAU inhibitor, it is involved in the regulation of cell adhesion and spreading. 1. Kortlever, RM. et al. (2006) Nature cell biology 8, 877-84. PMID: 16862142 2. Jiang, C. et al. (2017) Aging cell 16, 1114-1124. PMID: 28722352 | ||||
| Note | For research use only. |

SDS-PAGE for Anti-Mouse SERPINE1/PAI-1 Antibody (SAA0768).
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