Anti-Mouse SHH Recombinant Antibody (6D7) (MS826107)

Name: Anti-Mouse SHH Recombinant Antibody (6D7)
Brand: abinScience
SKU: MS826107
Price: 191 USD
Availability: InStock

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Overview

Catalog No.	MS826107
Species reactivity	Human, Mouse
Applications	ELISA, FCM
Host species	Rat
Isotype	IgG1, kappa
Clone ID	6D7
Clonality	Monoclonal
Target	ShhNC, Sonic hedgehog protein, Shh N-terminal processed signaling domains, SHH, Shh unprocessed N-terminal signaling and C-terminal autoprocessing domains, ShhN, ShhNp, HHG-1
Endotoxin level	Please contact with the lab for this information.
Purity	>95% as determined by SDS-PAGE.
Purification	Protein A/G purified from cell culture supernatant.
Accession	Q62226
Form	Liquid
Storage buffer	0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Background	Sonic hedgehog protein (SHH) is a ~47 kDa protein. The C-terminal part of the sonic hedgehog protein precursor displays an autoproteolysis and a cholesterol transferase activity. Both activities result in the cleavage of the full-length protein into two parts (ShhN and ShhC) followed by the covalent attachment of a cholesterol moiety to the C-terminal of the newly generated ShhN. Both activities occur in the reticulum endoplasmic. Once cleaved, ShhC is degraded in the endoplasmic reticulum. 1. Roelink, H. et al. (1995) Cell 81, 445-55. PMID: 7736596 2. Bumcrot, DA. et al. (1995) Molecular and cellular biology 15, 2294-303. PMID: 7891723 3. Porter, JA. et al. (1996) Science (New York, N.Y.) 274, 255-9. PMID: 8824192 4. Chen, X. et al. (2011) The Journal of cell biology 192, 825-38. PMID: 21357747
Note	For research use only.

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SDS-PAGE for Anti-Mouse SHH Antibody (6D7)

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Datasheet

Anti-Mouse SHH Recombinant Antibody (6D7).pdf

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Anti-Mouse SHH Recombinant Antibody (6D7) (MS826107)

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