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Anti-Mouse SIGIRR Polyclonal Antibody (MV050014)

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Overview
Catalog No.MV050014
Description
Anti-Mouse SIGIRR Polyclonal Antibody (MV050014) is a rabbit polyclonal antibody detecting SIGIRR in ELISA, IHC, WB. Suitable for Mouse.
Highlights
  • ●Affinity Purified — Minimal background and high purity for reliable results.
  • ●Multi-Application — Validated across multiple applications.
Species reactivityMouse, Rat
ApplicationsELISA, IHC, WB
Host speciesRabbit
IsotypeIgG
Clonality Polyclonal
Immunogen E. coli - derived recombinant Mouse SIGIRR (Ala2-His117).
Target TIR8, Toll/interleukin-1 receptor 8, Single Ig IL-1R-related molecule, Single Ig IL-1-related receptor, Single immunoglobulin domain-containing IL1R-related protein, SIGIRR
Purification Purified by antigen affinity column.
Accession Q9JLZ8
Form Liquid
Storage buffer 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Product Usage Information
Application Dilution
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Stability and Storage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Background

Single Ig IL-1-related receptor (SIGIRR) is a ~46 kDa protein. Acts as a negative regulator of the Toll-like and IL-1R receptor signaling pathways. Attenuates the recruitment of receptor-proximal signaling components to the TLR4 receptor, probably through an TIR-TIR domain interaction with TLR4. Through its extracellular domain interferes with the heterodimerization of Il1R1 and IL1RAP.

Note For research use only.
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Formula
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Working Solution
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Anti-Mouse SIGIRR Polyclonal Antibody

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