

| Catalog No. | MV203014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Description |
Anti-Mouse SIGLEC12 Polyclonal Antibody (MV203014) is a rabbit polyclonal antibody detecting SIGLEC12 in ELISA, IHC, WB. Suitable for Mouse.
Highlights
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| Species reactivity | Mouse | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Host species | Rabbit | ||||||||
| Isotype | IgG | ||||||||
| Clonality | Polyclonal | ||||||||
| Immunogen | E. coli - derived recombinant Mouse SIGLEC12 (Gln19-Ala253). | ||||||||
| Target | Sialic acid-binding Ig-like lectin 12, Siglec-L1, Sialic acid-binding Ig-like lectin-like 1, SIGLEC12, SLG, Siglec-12, SIGLECL1 | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Accession | Q91Y57 | ||||||||
| Form | Liquid | ||||||||
| Storage buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| Product Usage Information |
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| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Background | Sialic acid-binding Ig-like lectin 12 (SIGLEC12) is a ~51 kDa protein. Putative adhesion molecule that mediates sialic-acid dependent binding to cells. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. In the immune response, may act as an inhibitory receptor upon ligand induced tyrosine phosphorylation by recruiting cytoplasmic phosphatase(s) via their SH2 domain(s) that block signal transduction through dephosphorylation of signaling molecules. | ||||||||
| Note | For research use only. |
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