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Anti-Mouse TLR5 Polyclonal Antibody (MT266014)

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Overview
Catalog No.MT266014
Description
Anti-Mouse TLR5 Polyclonal Antibody (MT266014) is a rabbit polyclonal antibody detecting TLR5. Suitable for Mouse.
Species reactivityMouse
ApplicationsELISA, IHC, WB
Host speciesRabbit
IsotypeIgG
Clonality Polyclonal
Immunogen E. coli - derived recombinant Mouse TLR5 (Asp27-Leu292).
Target TIL3, TLR5, Toll-like receptor 5, Toll/interleukin-1 receptor-like protein 3
Endotoxin level Please contact with the lab for this information.
Purification Purified by antigen affinity column.
Accession Q9JLF7
Form Liquid
Storage buffer 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Product Usage Information
Application Dilution
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Background

Toll-like receptor 5 (TLR5) is a ~97 kDa protein. Pattern recognition receptor (PRR) located on the cell surface that participates in the activation of innate immunity and inflammatory response. Recognizes small molecular motifs named pathogen-associated molecular pattern (PAMPs) expressed by pathogens and microbe-associated molecular patterns (MAMPs) usually expressed by resident microbiota. Upon ligand binding such as bacterial flagellins, recruits intracellular adapter proteins MYD88 and TRIF leading to NF-kappa-B activation, cytokine secretion and induction of the inflammatory response. Plays thereby an important role in the relationship between the intestinal epithelium and enteric microbes and contributes to the gut microbiota composition throughout life.

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Anti-Mouse TLR5 Polyclonal Antibody

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