

| Catalog No. | VK094034 | ||||
|---|---|---|---|---|---|
| Description |
Anti-MRV-3 Outer capsid protein mu-1 Polyclonal Antibody (VK094034) is a rabbit polyclonal antibody detecting MRV-3 Outer capsid protein mu-1 in ELISA, IHC, WB. Suitable for Reovirus type 1, Reovirus type 2, and Reovirus type 3.
Highlights
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| Species reactivity | Mammalian orthoreovirus 1 (MRV1) | ||||
| Applications | ELISA, IHC, WB | ||||
| Host species | Rabbit | ||||
| Clonality | Polyclonal | ||||
| Isotype | IgG | ||||
| Immunogen | E. coli - derived recombinant MRV-3 Outer capsid protein mu-1 (Lys317-Ser500). | ||||
| Target | M2 | ||||
| Endotoxin level | Please contact with the lab for this information. | ||||
| Purity | >95% as determined by SDS-PAGE. | ||||
| Purification | Purified by antigen affinity column. | ||||
| Accession | P11077, P11078, P12397 | ||||
| Form | Liquid | ||||
| Storage buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| Product Usage Information |
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| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||
| Background | Outer capsid protein mu-1 is a ~76 kDa protein. Major outer capsid protein involved in host cell membrane penetration. In the endocytic compartment, outer-capsid protein sigma-3 is removed by cathepsin proteases, which exposes the viral membrane-penetration protein mu-1. Both myristoylated peptides mu-1N and phi are released during infectious subvirion particles (ISVP) formation in the endosome. They associate with host membranes and mu-1N induces permeabilization and delivery of transcriptionally active viral particles into the host cell cytoplasm. Seems to induce apoptosis in the host cell. | ||||
| Note | For research use only |
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