

| Catalog No. | HV552014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Description |
Anti-MSRA Polyclonal Antibody (HV552014) is a rabbit polyclonal antibody detecting MSRA in ELISA, IHC, WB. Suitable for Human, Mouse, Rat, and Bovine.
Highlights
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| Species reactivity | Human | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Host species | Rabbit | ||||||||
| Isotype | IgG | ||||||||
| Clonality | Polyclonal | ||||||||
| Immunogen | E. coli - derived recombinant Human MSRA (Ala27-Lys235). | ||||||||
| Target | Peptide-methionine (S)-S-oxide reductase, PMSR, Peptide Met(O) reductase, MSRA, Protein-methionine-S-oxide reductase, Mitochondrial peptide methionine sulfoxide reductase | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Accession | Q9UJ68 | ||||||||
| Form | Liquid | ||||||||
| Storage buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| Product Usage Information |
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| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Background | Mitochondrial peptide methionine sulfoxide reductase (MSRA) is a ~26 kDa protein. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Plays a crucial role in repairing oxidized methionine residues in key lens proteins, such as alpha-crystallin (CRYAA/CRYAB) and cytochrome c (CYCS), thereby restoring their function and maintaining lens transparency. 1. Kuschel, L. et al. (1999) FEBS letters 456, 17-21. PMID: 10452521 2. Hansel, A. et al. (2002) FASEB journal : official publication of the Federation of American Societies for Experimental Biology 16, 911-3. PMID: 12039877 | ||||||||
| Note | For research use only. |
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