Anti-MTA1 Polyclonal Antibody (HA784014)

Name: Anti-MTA1 Polyclonal Antibody
Brand: abinScience
SKU: HA784014
Price: 168 USD
Availability: InStock

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Overview
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References
Datasheet
SDS

Overview

Catalog No.

HA784014

Description

Anti-MTA1 Polyclonal Antibody (HA784014) is a rabbit polyclonal antibody detecting Metastasis-associated protein MTA1; MTA1 in ELISA, IHC, WB. Suitable for Human, Mouse, and Rat.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

Species reactivity

Human, Mouse, Rat

Applications

ELISA, IHC, WB

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Immunogen

E. coli - derived recombinant human MTA1 (Met1-Leu430).

Target

Metastasis-associated protein MTA1; MTA1

Endotoxin level

Please contact with the lab for this information.

Purification

Purified by antigen affinity column.

Accession

Q13330, Q8K4B0, Q62599

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Background

Metastasis-associated protein MTA1 is a ~80 kDa protein. Transcriptional coregulator which can act as both a transcriptional corepressor and coactivator. Acts as a component of the histone deacetylase NuRD complex which participates in the remodeling of chromatin. In the NuRD complex, regulates transcription of its targets by modifying the acetylation status of the target chromatin and cofactor accessibility to the target DNA. In conjunction with other components of NuRD, acts as a transcriptional corepressor of BRCA1, ESR1, TFF1 and CDKN1A. Acts as a transcriptional coactivator of BCAS3, and SUMO2, independent of the NuRD complex.

1. Gururaj, AE. et al. (2006) Proceedings of the National Academy of Sciences of the United States of America 103, 6670-5. PMID: 16617102

2. Balasenthil, S. et al. (2007) Cancer research 67, 7132-8. PMID: 17671180

3. Molli, PR. et al. (2008) Oncogene 27, 1971-80. PMID: 17922032

4. Cong, L. et al. (2011) The Journal of biological chemistry 286, 43793-43808. PMID: 21965678

5. Kang, HJ. et al. (2014) Cancer research 74, 1484-94. PMID: 24413532

6. Le Guezennec, X. et al. (2006) Molecular and cellular biology 26, 843-51. PMID: 16428440

7. Hoffmeister, H. et al. (2017) Nucleic acids research 45, 10534-10554. PMID: 28977666

8. Li, DQ. et al. (2009) The Journal of biological chemistry 284, 34545-52. PMID: 19837670

Note

For research use only

Images

References

Datasheet

Anti-MTA1 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

Assay Kits

Anti-MTA1 Polyclonal Antibody (HA784014)

Overview

Images

References

Datasheet

SDS