

| Catalog No. | HV495014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Description |
Anti-MTUS1 Polyclonal Antibody (HV495014) is a rabbit polyclonal antibody detecting MTUS1 in ELISA, IHC, WB. Suitable for Human, Mouse, Rat, Bovine, and Pongo abelii.
Highlights
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| Species reactivity | Human, Mouse | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Host species | Rabbit | ||||||||
| Clonality | Polyclonal | ||||||||
| Isotype | IgG | ||||||||
| Immunogen | E. coli - derived recombinant Human MTUS1 (Met1031-Arg1270). | ||||||||
| Target | AT2 receptor-binding protein, Angiotensin-II type 2 receptor-interacting protein, ATBP, Mitochondrial tumor suppressor 1, MTSG1, MTUS1, ATIP, Microtubule-associated tumor suppressor 1, GK1, KIAA1288 | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Accession | Q9ULD2 | ||||||||
| Form | Liquid | ||||||||
| Storage buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| Product Usage Information |
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| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Background | Microtubule-associated tumor suppressor 1 (MTUS1) is a ~141 kDa protein. Cooperates with AGTR2 to inhibit ERK2 activation and cell proliferation. May be required for AGTR2 cell surface expression. Together with PTPN6, induces UBE2V2 expression upon angiotensin-II stimulation. Isoform 1 inhibits breast cancer cell proliferation, delays the progression of mitosis by prolonging metaphase and reduces tumor growth. | ||||||||
| Note | For research use only. |
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