Anti-MX1 Polyclonal Antibody (HB647014)

Name: Anti-MX1 Polyclonal Antibody
Brand: abinScience
SKU: HB647014
Price: 168 USD
Availability: InStock

Datasheet Share product Copy info

Price(USD):

Spec:

50ug
100ug

Number:

Get quote

Overview
Images
References
Datasheet
SDS

Overview

Catalog No.

HB647014

Description

Anti-MX1 Polyclonal Antibody (HB647014) is a rabbit polyclonal antibody detecting MX1 in ELISA, IHC, WB. Suitable for Human, Macaca mulatta, and Pongo abelii.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

Species reactivity

Human, Macaca mulatta, Pongo abelii

Applications

ELISA, IHC, WB

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human MX1 (Glu366-Thr636).

Target

IFI-78K, Myxovirus resistance protein 1, Myxoma resistance protein 1, Interferon-induced GTP-binding protein Mx1, MX1, Interferon-induced protein p78, Interferon-regulated resistance GTP-binding protein MxA

Purification

Purified by antigen affinity column.

Accession

P20591

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Background

Interferon-induced GTP-binding protein Mx1 is a ~75 kDa protein. Interferon-induced dynamin-like GTPase with antiviral activity against a wide range of RNA viruses and some DNA viruses. Its target viruses include negative-stranded RNA viruses and HBV through binding and inactivation of their ribonucleocapsid. May also antagonize reoviridae and asfarviridae replication. Inhibits thogoto virus (THOV) replication by preventing the nuclear import of viral nucleocapsids. Inhibits La Crosse virus (LACV) replication by sequestering viral nucleoprotein in perinuclear complexes, preventing genome amplification, budding, and egress.

Note

For research use only.

Images