

| Catalog No. | JN930013 | ||||
|---|---|---|---|---|---|
| Species reactivity | Mycobacterium tuberculosis | ||||
| Applications | ELISA | ||||
| Host species | Human | ||||
| Isotype | IgG1 | ||||
| Clone ID | SAA2176 | ||||
| Clonality | Monoclonal | ||||
| Target | Isocitrate lyase 1, ICL1, 4.1.3.1, Isocitrase, Isocitratase, Methylisocitrate lyase, MICA, 4.1.3.30, icl1, ERDMAN_0512, Q643_00485, MT0483, Rv0467, MTV038.11 | ||||
| Endotoxin level | Please contact with the lab for this information. | ||||
| Purity | >95% as determined by SDS-PAGE. | ||||
| Purification | Protein A/G purified from cell culture supernatant. | ||||
| Accession | H8EVV4, P0A5H3, P9WKK6, P9WKK7 | ||||
| RRID | Anti-Mycobacterium tuberculosis icl1/Isocitrate lyase 1 Antibody (SAA2176) (abinScience Cat# JN930013, RRID:AB_3729542) |
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| Form | Liquid | ||||
| Storage buffer | 0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| Product Usage Information |
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| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. | ||||
| Background | Isocitrate lyase 1 (icl1) is a ~47 kDa protein. Involved in the persistence and virulence of M.tuberculosis. Catalyzes the reversible formation of succinate and glyoxylate from isocitrate, a key step of the glyoxylate cycle, which operates as an anaplerotic route for replenishing the tricarboxylic acid cycle during growth on fatty acid substrates. It also catalyzes the formation of pyruvate and succinate from 2-methylisocitrate, a key step in the methylcitrate cycle (propionate degradation route). | ||||
| Note | For research use only. |

SDS-PAGE for Anti-Mycobacterium tuberculosis icl1/Isocitrate lyase 1 Antibody (SAA2176)
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