

| Catalog No. | HC094014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Description |
Anti-NACA Polyclonal Antibody (HC094014) is a rabbit polyclonal antibody detecting NACA in ELISA, IHC, WB. Suitable for Bovine, Mouse, Human, Frog, and Zebrafish.
Highlights
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| Species reactivity | Human, Mouse | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Host species | Rabbit | ||||||||
| Isotype | IgG | ||||||||
| Clonality | Polyclonal | ||||||||
| Immunogen | E. coli - derived recombinant NACA (Pro63-Met215). | ||||||||
| Target | Nascent polypeptide-associated complex subunit alpha, NAC-alpha, Alpha-NAC, Hom s 2, NACA | ||||||||
| Endotoxin level | Please contact with the lab for this information. | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Accession | Q5E9A1, Q60817, P70670, E9PAV3, Q13765, Q6IP73, Q8JIU7, Q9H009, Q9BZK3 | ||||||||
| Form | Liquid | ||||||||
| Storage buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| Product Usage Information |
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| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Background | Nascent polypeptide-associated complex subunit alpha is a ~23 kDa protein. Prevents inappropriate targeting of non-secretory polypeptides to the endoplasmic reticulum (ER). Binds to nascent polypeptide chains as they emerge from the ribosome and blocks their interaction with the signal recognition particle (SRP), which normally targets nascent secretory peptides to the ER. Also reduces the inherent affinity of ribosomes for protein translocation sites in the ER membrane (M sites). May act as a specific coactivator for JUN, binding to DNA and stabilizing the interaction of JUN homodimers with target gene promoters. | ||||||||
| Note | For research use only |
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