

| Catalog No. | HV364014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Description |
Anti-NEIL1 Polyclonal Antibody (HV364014) is a rabbit polyclonal antibody detecting NEIL1 in ELISA, IHC, WB. Suitable for Human and Mouse.
Highlights
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| Species reactivity | Human | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Host species | Rabbit | ||||||||
| Clonality | Polyclonal | ||||||||
| Isotype | IgG | ||||||||
| Immunogen | E. coli - derived recombinant Human NEIL1 (Ser43-Ala314). | ||||||||
| Target | Endonuclease 8-like 1, DNA glycosylase/AP lyase Neil1, Endonuclease VIII-like 1, Nei-like protein 1, DNA-(apurinic or apyrimidinic site) lyase Neil1, Nei homolog 1, NEIL1, FPG1, NEH1 | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Accession | Q96FI4 | ||||||||
| Form | Liquid | ||||||||
| Storage buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| Product Usage Information |
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| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Background | Endonuclease 8-like 1 (NEIL1) is a ~43 kDa protein. Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as a DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized pyrimidines, such as thymine glycol, formamidopyrimidine (Fapy) and 5-hydroxyuracil. Has marginal activity towards 8-oxoguanine. Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. | ||||||||
| Note | For research use only. |
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