

| Catalog No. | HV562014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Species reactivity | Human | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Host species | Rabbit | ||||||||
| Isotype | IgG | ||||||||
| Clonality | Polyclonal | ||||||||
| Immunogen | E. coli - derived recombinant Human NEO1 (Pro52-Ile426). | ||||||||
| Target | IGDCC2, NEO1, Neogenin, NGN, Immunoglobulin superfamily DCC subclass member 2 | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Accession | Q92859 | ||||||||
| Form | Liquid | ||||||||
| Storage buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| Product Usage Information |
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| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Background | Neogenin (NEO1) is a ~160 kDa protein. Multi-functional cell surface receptor regulating cell adhesion in many diverse developmental processes, including neural tube and mammary gland formation, myogenesis and angiogenesis. Receptor for members of the BMP, netrin, and repulsive guidance molecule (RGM) families. Netrin-Neogenin interactions result in a chemoattractive axon guidance response and cell-cell adhesion, the interaction between NEO1/Neogenin and RGMa and RGMb induces a chemorepulsive response. | ||||||||
| Note | For research use only. |

Western blot analysis was performed using anti-NEO1 polyclonal antibody at 1μg/ml on various samples.
Lane 1: Jurkat cell lysate
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