

| Catalog No. | HW303014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Species reactivity | Human, Mouse, Rat | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Host species | Rabbit | ||||||||
| Clonality | Polyclonal | ||||||||
| Isotype | IgG | ||||||||
| Immunogen | E. coli - derived recombinant Human NR4A2 (Met1-Thr335). | ||||||||
| Target | Transcriptionally-inducible nuclear receptor, NURR1, NR4A2, NOT, Nuclear receptor subfamily 4 group A member 2, Orphan nuclear receptor NURR1, TINUR, Immediate-early response protein NOT | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Accession | P43354 | ||||||||
| Form | Liquid | ||||||||
| Storage buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| Product Usage Information |
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| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Background | Nuclear receptor subfamily 4 group A member 2 (NR4A2) is a ~66 kDa protein. Transcriptional regulator which is important for the differentiation and maintenance of meso-diencephalic dopaminergic (mdDA) neurons during development. It is crucial for expression of a set of genes such as SLC6A3, SLC18A2, TH and DRD2 which are essential for development of mdDA neurons. 1. Flaig, R. et al. (2005) The Journal of biological chemistry 280, 19250-8. PMID: 15716272 2. Messmer, K. et al. (2007) International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience 25, 29-37. PMID: 17184956 | ||||||||
| Note | For research use only. |
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