

| Catalog No. | HV965014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Description |
Anti-NUP50 Polyclonal Antibody (HV965014) is a rabbit polyclonal antibody detecting NUP50 in ELISA, IHC, WB. Suitable for Human.
Highlights
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| Species reactivity | Human | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Host species | Rabbit | ||||||||
| Isotype | IgG | ||||||||
| Clonality | Polyclonal | ||||||||
| Immunogen | E. coli - derived recombinant Human NUP50 (Asn37-Ala269). | ||||||||
| Target | Nuclear pore complex protein Nup50, 50 kDa nucleoporin, NUP50, Nuclear pore-associated protein 60 kDa-like, NPAP60L, Nucleoporin Nup50 | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Accession | Q9UKX7 | ||||||||
| Form | Liquid | ||||||||
| Storage buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| Product Usage Information |
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| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Background | Nuclear pore complex protein Nup50 is a ~50 kDa protein. Component of the nuclear pore complex that has a direct role in nuclear protein import. Actively displaces NLSs from importin-alpha, and facilitates disassembly of the importin-alpha:beta-cargo complex and importin recycling. Interacts with regulatory proteins of cell cycle progression including CDKN1B. This interaction is required for correct intracellular transport and degradation of CDKN1B. 1. Ogawa, Y. et al. (2010) Molecular biology of the cell 21, 630-8. PMID: 20016008 | ||||||||
| Note | For research use only. |
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