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Anti-Omalizumab Non-Neutralizing Recombinant Antibody (SAA2619) (AV064013)

Anti-Omalizumab Non-Neutralizing Recombinant Antibody (SAA2619)
Anti-Omalizumab Non-Neutralizing Recombinant Antibody (SAA2619)
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Overview
Catalog No.AV064013
Description
Anti-Omalizumab Non-Neutralizing Recombinant Antibody (SAA2619) (AV064013) is a rabbit monoclonal antibody detecting Dupilumab in ELISA. Suitable for General.
Highlights
  • ●Affinity Purified — Minimal background and high purity for reliable results.
Species reactivityGeneral
ApplicationsELISA
Host speciesRabbit
ClonalityMonoclonal
IsotypeIgG
Clone IDSAA2619
Expression system Mammalian cells
Immunogen Omalizumab
Endotoxin level < 10 EU/mg as determined by LAL method.
Purity >95% as determined by SDS-PAGE.
Purification Protein A/G purified from cell culture supernatant.
Accession CAS: 242138-07-4
Form Liquid
Storage buffer 0.01M PBS pH 7.4.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information
Application Dilution
ELISA 1:2000-1:20000
Stability and Storage Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Background

Interleukin-4 receptor subunit alpha (Dupilumab) is a ~89 kDa protein. Receptor for both interleukin 4 and interleukin 13. Couples to the JAK1/2/3-STAT6 pathway. The IL4 response is involved in promoting Th2 differentiation. The IL4/IL13 responses are involved in regulating IgE production and, chemokine and mucus production at sites of allergic inflammation. In certain cell types, can signal through activation of insulin receptor substrates, IRS1/IRS2.

1. Andrews, AL. et al. (2006) The Journal of allergy and clinical immunology 118, 858-65. PMID: 17030238
Note For research use only.
Images
  • Anti-Omalizumab Non-Neutralizing Recombinant Antibody (SAA2619)

    Bioactivity

    Detects Omalizumab in indirect ELISA.

References
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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