Anti-OPG199 Polyclonal Antibody (VK070014)

Name: Anti-OPG199 Polyclonal Antibody
Brand: abinScience
SKU: VK070014
Price: 168 USD
Availability: InStock

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Overview

Catalog No.

VK070014

Description

Anti-OPG199 Polyclonal Antibody (VK070014) is a rabbit polyclonal antibody detecting OPG199 in ELISA, IHC, WB. Suitable for Variola virus, Cowpox virus, Rabbitpox virus, Monkeypox virus, and Vaccinia virus.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

Species reactivity

Variola virus, Cowpox virus, Rabbitpox virus, Monkeypox virus, Vaccinia virus

Applications

ELISA, IHC, WB

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant cpxv OPG199 (Met1-Leu300).

Target

CrmA or CPXV207 protein, CrmA

Endotoxin level

Please contact with the lab for this information.

Purification

Purified by antigen affinity column.

Accession

P07385, A0A7H0DNF9, P42926, P0DSW4, P20842, P15059, P0DSW3, P20841

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Background

Serine proteinase inhibitor 2 (OPG199) is a ~38 kDa protein. Viral serpin that inhibits both cysteine and serine proteinases involved in the regulation of host inflammatory and apoptosis processes. Major anti-apoptotic protein which inhibits both intrinsic and extrinsic pathways and strongly cleaves host CASP1 and CASP8 but is a rather poor inhibitor of host CASP3. Prevents the proteolytic activity of host interleukin-1-beta converting enzyme (ICE) and ICE-like enzymes. Can also block apoptosis through host tumor necrosis factor (TNF) receptor.

1. Simonovic, M. et al. (2000) Protein science : a publication of the Protein Society 9, 1423-7. PMID: 10975564

2. Renatus, M. et al. (2000) Structure (London, England : 1993) 8, 789-97. PMID: 10903953

Note

For research use only

Images

References

Datasheet

Anti-OPG199 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

Assay Kits

Anti-OPG199 Polyclonal Antibody (VK070014)

Overview

Images

References

Datasheet

SDS

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