

| Catalog No. | HY133014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Description |
Anti-PAEP Polyclonal Antibody (HY133014) is a rabbit polyclonal antibody detecting PAEP in ELISA, IHC, WB. Suitable for Human.
Highlights
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| Species reactivity | Human | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Host species | Rabbit | ||||||||
| Clonality | Polyclonal | ||||||||
| Isotype | IgG | ||||||||
| Immunogen | E. coli - derived recombinant Human PAEP (Met19-Phe158). | ||||||||
| Target | PAEG, Progestagen-associated endometrial protein, Pregnancy-associated endometrial alpha-2 globulin, GD, PEG, PAEP, Progesterone-associated endometrial protein, ZIF-1, PP14, Placental protein 14, Glycodelin, Zona-binding inhibitory factor-1 | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Accession | P09466 | ||||||||
| Form | Liquid | ||||||||
| Storage buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| Product Usage Information |
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| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Background | Glycodelin (PAEP) is a ~20 kDa protein. Glycoprotein that regulates critical steps during fertilization and also has immunomonomodulatory effects. Four glycoforms, namely glycodelin-S, -A, -F and -C have been identified in reproductive tissues that differ in glycosylation and biological activity. Glycodelin-A has contraceptive and immunosuppressive activities. Glycodelin-C stimulates binding of spermatozoa to the zona pellucida. Glycodelin-F inhibits spermatozoa-zona pellucida binding and significantly suppresses progesterone-induced acrosome reaction of spermatozoa. 1. Oehninger, S. et al. (1995) Fertility and sterility 63, 377-83. PMID: 7531163 2. Rachmilewitz, J. et al. (1999) Cellular immunology 191, 26-33. PMID: 9918684 3. Chiu, PC. et al. (2007) The Journal of biological chemistry 282, 5378-88. PMID: 17192260 4. Chiu, PC. et al. (2003) Biology of reproduction 69, 365-72. PMID: 12672671 5. Chiu, PC. et al. (2005) The Journal of biological chemistry 280, 25580-9. PMID: 15883155 | ||||||||
| Note | For research use only. |
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