Anti-pan-Glypican Recombinant Antibody (HS20) (HW310063)

Name: Anti-pan-Glypican Recombinant Antibody (HS20)
Brand: abinScience
SKU: HW310063
Price: 191 USD
Availability: InStock

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50ug
100ug
1mg

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Overview
Images
References
Datasheet
SDS

Overview

Catalog No.

HW310063

Species reactivity

Human

Applications

ELISA, FACS, Functional assay

Host species

Human

Isotype

IgG1, kappa

Clone ID

HS20

Clonality

Monoclonal

Target

pan-Glypican, heparan sulfate, Glypican-1, Secreted glypican-1, GPC1, Glypican-2, Secreted glypican-2, GPC2, Glypican-3, GTR2-2, Intestinal protein OCI-5, MXR7, Glypican-3 alpha subunit, Glypican-3 beta subunit, GPC3, OCI5, Glypican-4, K-glypican, Secreted glypican-4, GPC4, Glypican-5, Secreted glypican-5, GPC5, Glypican-6, Secreted glypican-6, GPC6

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

P35052, Q8N158, I6QTG3, O75487, P78333, Q9Y625

Form

Liquid

Storage buffer

0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:2000-1:20000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Background

Glypican-1 (pan-Glypican) is a ~61 kDa protein. Cell surface proteoglycan that bears heparan sulfate. Binds, via the heparan sulfate side chains, alpha-4 (V) collagen and participates in Schwann cell myelination. May act as a catalyst in increasing the rate of conversion of prion protein PRPN(C) to PRNP(Sc) via associating (via the heparan sulfate side chains) with both forms of PRPN, targeting them to lipid rafts and facilitating their interaction. Required for proper skeletal muscle differentiation by sequestering FGF2 in lipid rafts preventing its binding to receptors (FGFRs) and inhibiting the FGF-mediated signaling.

Note

For research use only

Images

SDS-PAGE

SDS-PAGE for Anti-pan-Glypican Antibody (HS20)

References

Datasheet

Anti-pan-Glypican Recombinant Antibody (HS20).pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

Assay Kits

Anti-pan-Glypican Recombinant Antibody (HS20) (HW310063)

Overview

Images

References

Datasheet

SDS

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