Anti-Pan HBV S/L-HBsAg/L glycoprotein Recombinant Antibody (KR127) (VK539023)

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Datasheet
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Overview

Catalog No.

VK539023

Description

Anti-Pan HBV S/L-HBsAg/L glycoprotein Antibody (KR127) [KR127] (VK539023) is a human monoclonal antibody detecting L glycoprotein in ELISA, WB.

Species reactivity

Hepatitis B virus (HBV) (Q2EID8), Hepatitis B virus genotype A2 subtype adw (isolate Japan/Nishioka/1983)(HBV-A) (P03142), Hepatitis B virus genotype D subtype adw (isolate United Kingdom/adyw/1979)(HBV-D) (P03139), Hepatitis B virus (HBV) (Q96836), Hepatitis B virus (HBV) (Q86986), Hepatitis B virus (HBV) (Q81186), Hepatitis B virus genotype C subtype adr (isolate Korea/Kim/1989) (HBV-C) (Q67867)

Applications

ELISA, WB

Host species

Human

Isotype

IgG1

Clone ID

KR127

Clonality

Monoclonal

Target

Large envelope protein S, L glycoprotein, L-HBsAg, LHB, Large surface protein, Major surface protein, preS1 domain, Pre-S1

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

P03142

RRID

Anti-Pan HBV S/L-HBsAg/L glycoprotein Antibody (KR127) (abinScience Cat# VK539023, RRID:AB_3726928)

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:2000-1:20000
WB	1:500-1:2000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Background

Large envelope protein (HBsAg) is a ~42 kDa protein. The large envelope protein exists in two topological conformations, one which is termed 'external' or Le-HBsAg and the other 'internal' or Li-HBsAg. In its external conformation the protein attaches the virus to cell receptors and thereby initiating infection. This interaction determines the species specificity and liver tropism. This attachment induces virion internalization predominantly through caveolin-mediated endocytosis. The large envelope protein also assures fusion between virion membrane and endosomal membrane.

Note

For research use only.

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