

| Catalog No. | HV218014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Description |
Anti-PCYOX1 Polyclonal Antibody (HV218014) is a rabbit polyclonal antibody detecting PCYOX1 in ELISA, IHC, WB. Suitable for Human, Macaca fascicularis, and Pongo abelii.
Highlights
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| Species reactivity | Human | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Host species | Rabbit | ||||||||
| Clonality | Polyclonal | ||||||||
| Isotype | IgG | ||||||||
| Immunogen | E. coli - derived recombinant Human PCYOX1 (Tyr174-Leu505). | ||||||||
| Target | Prenylcysteine oxidase 1, Prenylcysteine lyase, PCYOX1, KIAA0908, PCL1 | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Accession | Q9UHG3 | ||||||||
| Form | Liquid | ||||||||
| Storage buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| Product Usage Information |
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| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Background | Prenylcysteine oxidase 1 (PCYOX1) is a ~56 kDa protein. Prenylcysteine oxidase that cleaves the thioether bond of prenyl-L-cysteines, such as farnesylcysteine and geranylgeranylcysteine. Only active against free prenylcysteines and not prenylcysteine residues within prenylated proteins or peptides. Involved in the final step in the degradation of prenylated proteins, by degrading prenylcysteines after the protein has been degraded. 1. Tschantz, WR. et al. (1999) The Journal of biological chemistry 274, 35802-8. PMID: 10585463 2. Tschantz, WR. et al. (2001) The Journal of biological chemistry 276, 2321-4. PMID: 11078725 3. Digits, JA. et al. (2002) The Journal of biological chemistry 277, 41086-93. PMID: 12186880 | ||||||||
| Note | For research use only. |
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