

| Catalog No. | HW378014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Species reactivity | Human, Mouse, Rat | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Host species | Rabbit | ||||||||
| Clonality | Polyclonal | ||||||||
| Isotype | IgG | ||||||||
| Immunogen | E. coli - derived recombinant Human PITPNB (Met1-Val271). | ||||||||
| Target | Phosphatidylinositol transfer protein beta isoform, PtdInsTP beta, PI-TP-beta, PtdIns transfer protein beta, PITPNB | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Accession | P48739 | ||||||||
| Form | Liquid | ||||||||
| Storage buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| Product Usage Information |
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| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Background | Phosphatidylinositol transfer protein beta isoform (PITPNB) is a ~31 kDa protein. Catalyzes the transfer of phosphatidylinositol and phosphatidylcholine between membranes. Also catalyzes the transfer of sphingomyelin. Required for COPI-mediated retrograde transport from the Golgi to the endoplasmic reticulum; phosphatidylinositol and phosphatidylcholine transfer activity is essential for this function. 1. Fullwood, Y. et al. (1999) The Journal of biological chemistry 274, 31553-8. PMID: 10531358 2. Shadan, S. et al. (2008) Traffic (Copenhagen, Denmark) 9, 1743-56. PMID: 18636990 3. Carvou, N. et al. (2010) Journal of cell science 123, 1262-73. PMID: 20332109 | ||||||||
| Note | For research use only. |
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