Anti-PITRM1 Polyclonal Antibody (HV687014)

Name: Anti-PITRM1 Polyclonal Antibody
Brand: abinScience
SKU: HV687014
Price: 96 USD
Availability: InStock

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Overview
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References
Datasheet
SDS

Overview

Catalog No.

HV687014

Description

Anti-PITRM1 Polyclonal Antibody (HV687014) is a rabbit polyclonal antibody detecting PITRM1 in ELISA, IHC, WB. Suitable for Human, Mouse, and Pongo abelii.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

Species reactivity

Human

Applications

ELISA, IHC, WB

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Immunogen

E. coli - derived recombinant Human PITRM1 (Leu544-Ser806).

Target

Pitrilysin metalloproteinase 1, hMP1, MP1, Metalloprotease 1, PREP, KIAA1104, Presequence protease, mitochondrial, PITRM1, hPreP

Purification

Purified by antigen affinity column.

Accession

Q5JRX3

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Background

Presequence protease, mitochondrial (PITRM1) is a ~117 kDa protein. Metalloendopeptidase of the mitochondrial matrix that functions in peptide cleavage and degradation rather than in protein processing. Has an ATP-independent activity. Specifically cleaves peptides in the range of 5 to 65 residues. Shows a preference for cleavage after small polar residues and before basic residues, but without any positional preference. Degrades the transit peptides of mitochondrial proteins after their cleavage.

1. Mzhavia, N. et al. (1999) DNA and cell biology 18, 369-80. PMID: 10360838

2. Falkevall, A. et al. (2006) The Journal of biological chemistry 281, 29096-104. PMID: 16849325

3. Chow, KM. et al. (2009) Biochemistry 48, 2868-77. PMID: 19196155

4. King, JV. et al. (2014) Structure (London, England : 1993) 22, 996-1007. PMID: 24931469

Note

For research use only.

Images

Western blot

Western blot analysis was performed using anti-PITRM1 polyclonal antibody at 1μg/ml on various samples.
Lane 1: MCF7 cell lysate
Lane 2: 293T cell lysate
Lane 3: Mouse kidney lysate

References

Datasheet

Anti-PITRM1 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

Assay Kits

Anti-PITRM1 Polyclonal Antibody (HV687014)

Overview

Images

References

Datasheet

SDS

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