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Anti-Plasmodium falciparum CSP Recombinant Antibody (SAA2601) (JN160023)

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Overview
Catalog No.JN160023
Species reactivityPlasmodium falciparum
ApplicationsELISA, Neutralization
IsotypeIgG1, kappa
Clone IDSAA2601
Clonality Monoclonal
Target CS, CSP, Circumsporozoite protein, Circumsporozoite protein C-terminus, PfCSP
Endotoxin level Please contact with the lab for this information.
Purity >95% as determined by SDS-PAGE.
Purification Protein A/G purified from cell culture supernatant.
Accession Q7K740
Form Liquid
Storage buffer 0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information
Application Dilution
ELISA 1:2000-1:20000
Stability and Storage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Background

Circumsporozoite protein (CSP) is a ~42 kDa protein. Essential sporozoite protein. In the mosquito vector, required for sporozoite development in the oocyst, migration through the vector hemolymph and entry into the vector salivary glands. In the vertebrate host, required for sporozoite migration through the host dermis and infection of host hepatocytes. Binds to highly sulfated heparan sulfate proteoglycans (HSPGs) on the surface of host hepatocytes.

1. Tan, J. et al. (2018) Nature medicine 24, 401-407. PMID: 29554084
2. Oyen, D. et al. (2020) PLoS pathogens 16, e1008373. PMID: 32150583
Note For research use only
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Formula
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