Anti-Poliovirus Capsid protein Recombinant Antibody (SAA2401) (VK557023)

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Overview

Catalog No.

VK557023

Description

Anti-Poliovirus Capsid protein Antibody (SAA2401) [SAA2401] (VK557023) is a human monoclonal antibody detecting Capsid protein VP0 in ELISA, Neutralization.

Species reactivity

Poliovirus type 1 (PV1)

Applications

ELISA, Neutralization

Host species

Human

Isotype

IgG1

Clone ID

SAA2401

Clonality

Monoclonal

Target

Genome polyprotein, P1, Capsid protein VP0, VP4-VP2, Capsid protein VP4, P1A, Virion protein 4, Capsid protein VP2, P1B, Virion protein 2, Capsid protein VP3, P1C, Virion protein 3, Capsid protein VP1

Endotoxin level

<10 EU/mg

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

P03301, P03300, Q8B3S1, P03302, P06210

Form

Liquid

Storage buffer

0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:2000-1:20000

Background

Genome polyprotein (Capsid) is a ~246 kDa protein. Forms an icosahedral capsid of pseudo T=3 symmetry with capsid proteins VP2 and VP3. The capsid is 300 Angstroms in diameter, composed of 60 copies of each capsid protein and enclosing the viral positive strand RNA genome. Capsid protein VP1 mainly forms the vertices of the capsid. Capsid protein VP1 interacts with host cell receptor PVR to provide virion attachment to target host cells. This attachment induces virion internalization predominantly through clathrin- and caveolin-independent endocytosis in Hela cells and through caveolin-mediated endocytosis in brain microvascular endothelial cells.

Note

For research use only

Images

SDS-PAGE

SDS-PAGE for Anti-Poliovirus Capsid protein Antibody (SAA2401)

References

Datasheet

Anti-Poliovirus Capsid protein Recombinant Antibody (SAA2401).pdf

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Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

Assay Kits

Anti-Poliovirus Capsid protein Recombinant Antibody (SAA2401) (VK557023)

Overview

Images

References

Datasheet

SDS

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