

| Catalog No. | HP567014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Species reactivity | Human | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Host species | Rabbit | ||||||||
| Isotype | IgG | ||||||||
| Clonality | Polyclonal | ||||||||
| Immunogen | E. coli - derived recombinant Human POLR1H (Met1-Ser126). | ||||||||
| Target | Zinc ribbon domain-containing protein 1, ZNRD1, RPA12, POLR1H, DNA-directed RNA polymerase I subunit H, DNA-directed RNA polymerase I subunit RPA12 | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Accession | Q9P1U0 | ||||||||
| Form | Liquid | ||||||||
| Storage buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| Product Usage Information |
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| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Background | DNA-directed RNA polymerase I subunit RPA12 (POLR1H) is a ~13 kDa protein. Core component of RNA polymerase I (Pol I), a DNA-dependent RNA polymerase which synthesizes ribosomal RNA precursors using the four ribonucleoside triphosphates as substrates. Can mediate Pol I proofreading of the nascent RNA transcript. Anchors into the Pol I active site to monitor transcription fidelity and cleave mis-incorporated 5'-ribonucleotides. | ||||||||
| Note | For research use only. |

Western blot analysis was performed using anti-POLR1H polyclonal antibody at 1ug/mL on recombinant POLR1H (Catalog No. HP567012).
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