

| Catalog No. | HV565014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Description |
Anti-PROX1 Polyclonal Antibody (HV565014) is a rabbit polyclonal antibody detecting PROX1 in ELISA, IHC, WB. Suitable for Human, Mouse, and Chicken.
Highlights
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| Species reactivity | Human, Mouse | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Host species | Rabbit | ||||||||
| Clonality | Polyclonal | ||||||||
| Isotype | IgG | ||||||||
| Immunogen | E. coli - derived recombinant Human PROX1 (Thr546-His736). | ||||||||
| Target | PROX1, Prospero homeobox protein 1, PROX-1, Homeobox prospero-like protein PROX1 | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Accession | Q92786 | ||||||||
| Form | Liquid | ||||||||
| Storage buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| Product Usage Information |
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| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Background | Prospero homeobox protein 1 (PROX1) is a ~83 kDa protein. Transcription factor involved in developmental processes such as cell fate determination, gene transcriptional regulation and progenitor cell regulation in a number of organs. Plays a critical role in embryonic development and functions as a key regulatory protein in neurogenesis and the development of the heart, eye lens, liver, pancreas and the lymphatic system. Involved in the regulation of the circadian rhythm. Represses: transcription of the retinoid-related orphan receptor RORG, transcriptional activator activity of RORA and RORG and the expression of RORA/G-target genes including core clock components: BMAL1, NPAS2 and CRY1 and metabolic genes: AVPR1A and ELOVL3. | ||||||||
| Note | For research use only. |
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