

| Catalog No. | HW628014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Description |
Anti-PSMC2 Polyclonal Antibody (HW628014) is a rabbit polyclonal antibody detecting PSMC2 in ELISA, IHC, WB. Suitable for Bovine, Human, Macaca fascicularis, Mouse, and Pongo abelii.
Highlights
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| Species reactivity | Human, Mouse, Rat | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Host species | Rabbit | ||||||||
| Isotype | IgG | ||||||||
| Clonality | Polyclonal | ||||||||
| Immunogen | E. coli - derived recombinant Human PSMC2 (Met1-Asn433). | ||||||||
| Target | MSS1, Protein MSS1, Proteasome 26S subunit ATPase 2, 26S proteasome AAA-ATPase subunit RPT1, PSMC2, 26S proteasome regulatory subunit 7 | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Accession | P35998 | ||||||||
| Form | Liquid | ||||||||
| Storage buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| Product Usage Information |
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| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Background | 26S proteasome regulatory subunit 7 (PSMC2) is a ~48 kDa protein. Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair. PSMC2 belongs to the heterohexameric ring of AAA (ATPases associated with diverse cellular activities) proteins that unfolds ubiquitinated target proteins that are concurrently translocated into a proteolytic chamber and degraded into peptides. | ||||||||
| Note | For research use only. |
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