Anti-PTGES2 Polyclonal Antibody (HV079014)

Name: Anti-PTGES2 Polyclonal Antibody
Brand: abinScience
SKU: HV079014
Price: 96 USD
Availability: InStock

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Datasheet
SDS

Overview

Catalog No.

HV079014

Description

Anti-PTGES2 Polyclonal Antibody (HV079014) is a rabbit polyclonal antibody detecting PTGES2 in ELISA, IHC, WB. Suitable for Human, Mouse, Bovine, and Macaca fascicularis.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

Species reactivity

Human

Applications

ELISA, IHC, WB

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Immunogen

E. coli - derived recombinant Human PTGES2 (Tyr145-Thr357).

Target

Microsomal prostaglandin E synthase 2, PGES2, Membrane-associated prostaglandin E synthase-2, Prostaglandin E synthase 2, Prostaglandin-H(2) E-isomerase, C9orf15, mPGES-2, mPGE synthase-2, PTGES2

Purification

Purified by antigen affinity column.

Accession

Q9H7Z7

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Background

Prostaglandin E synthase 2 (PTGES2) is a ~41 kDa protein. Isomerase that catalyzes the conversion of PGH2 into the more stable prostaglandin E2 (PGE2) (in vitro). The biological function and the GSH-dependent property of PTGES2 is still under debate. In vivo, PTGES2 could form a complex with GSH and heme and would not participate in PGE2 synthesis but would catalyze the degradation of prostaglandin E2 H2 (PGH2) to 12(S)-hydroxy-5(Z),8(E),10(E)-heptadecatrienoic acid (HHT) and malondialdehyde (MDA).

1. Watanabe, K. et al. (2003) Biochemical and biophysical research communications 306, 577-81. PMID: 12804604

2. Yamada, T. et al. (2007) Biochemistry 46, 8414-24. PMID: 17585783

3. Watanabe, K. et al. (2008) Biochemical and biophysical research communications 367, 782-6. PMID: 18198127

Note

For research use only.

Images

Western blot

Western blot analysis was performed using anti-PTGES2 polyclonal antibody at 1ug/mL on various samples.
Lane 1: Mouse heart lysate
Lane 2: Rat heart lysate

References

Datasheet

Anti-PTGES2 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

Assay Kits

Anti-PTGES2 Polyclonal Antibody (HV079014)

Overview

Images

References

Datasheet

SDS

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