Anti-RAB1A Polyclonal Antibody (HX207014)

Name: Anti-RAB1A Polyclonal Antibody
Brand: abinScience
SKU: HX207014
Price: 168 USD
Availability: InStock

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SDS

Overview

Catalog No.

HX207014

Species reactivity

Human, Mouse, Rat

Applications

ELISA, IHC, WB

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human RAB1A (Met1-Cys205).

Target

Ras-related protein Rab-1A, YPT1-related protein, RAB1A, RAB1

Purification

Purified by antigen affinity column.

Accession

P62820

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Background

Ras-related protein Rab-1A (RAB1A) is a ~22 kDa protein. The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. RAB1A regulates vesicular protein transport from the endoplasmic reticulum (ER) to the Golgi compartment and on to the cell surface, and plays a role in IL-8 and growth hormone secretion. Required to modulate the compacted morphology of the Golgi. Regulates the level of CASR present at the cell membrane.

1. Wang, C. et al. (2010) The Journal of biological chemistry 285, 29398-405. PMID: 20639577

2. Zhuang, X. et al. (2010) Endocrinology 151, 5114-23. PMID: 20861236

3. Mukhopadhyay, A. et al. (2011) Journal of cell science 124, 765-75. PMID: 21303926

4. Dong, N. et al. (2012) Cell 150, 1029-41. PMID: 22939626

5. Aizawa, M. et al. (2015) The Journal of biological chemistry 290, 22250-61. PMID: 26209634

Note

For research use only.

Images

References

Datasheet

Anti-RAB1A Polyclonal Antibody.pdf

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Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

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Assay Kits

Anti-RAB1A Polyclonal Antibody (HX207014)

Overview

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References

Datasheet

SDS

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