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Anti-RAB37 Polyclonal Antibody (HV558014)

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Overview
Catalog No.HV558014
Species reactivityHuman, Mouse
ApplicationsELISA, IHC, WB
Host speciesRabbit
ClonalityPolyclonal
IsotypeIgG
Immunogen E. coli - derived recombinant Human RAB37 (Ser19-Cys220).
Target Ras-related protein Rab-37, RAB37
Purification Purified by antigen affinity column.
Accession Q96AX2
Form Liquid
Storage buffer 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Product Usage Information
Application Dilution
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Stability and Storage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Background

Ras-related protein Rab-37 (RAB37) is a ~24 kDa protein. The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. Acts as an organizer for autophagosome biogenesis in a GTP-dependent manner. Involved in retinal homeostasis by autophagy regulation.

1. Ying, R. et al. (2024) Cell reports 43, 114010. PMID: 38536817
Note For research use only.
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Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
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V₁ (Stock Vol.)
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Working Solution
C₂ (Working Conc.)
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Anti-RAB37 Polyclonal Antibody

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