

| Catalog No. | HB399014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Description |
Anti-RAB5C Polyclonal Antibody (HB399014) is a rabbit polyclonal antibody detecting Ras-related protein Rab-5C; 3.6.5.2; L1880; RAB5L; RAB5C; RABL in ELISA, IHC, WB. Suitable for Mouse, Dog, Human, Bovine, and Chicken.
Highlights
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| Species reactivity | Human, Mouse, Rat | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Host species | Rabbit | ||||||||
| Isotype | IgG | ||||||||
| Clonality | Polyclonal | ||||||||
| Immunogen | E. coli - derived recombinant human RAB5C (Asn17-Leu182). | ||||||||
| Target | Ras-related protein Rab-5C; 3.6.5.2; L1880; RAB5L; RAB5C; RABL | ||||||||
| Endotoxin level | Please contact with the lab for this information. | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Accession | P35278, P51147, P51148, Q58DS9, Q98932, Q9CQD1, Q06AU6, Q0IIG7, P20339, P18066, M0RC99, Q5ZHW4, P61020, P61021 | ||||||||
| Form | Liquid | ||||||||
| Storage buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| Product Usage Information |
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| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Background | Ras-related protein Rab-5C (RAB5C) is a ~23 kDa protein. The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. Involved in early endocytic trafficking. Required for EEA1 recruitment to early endosomes. Required for EGF and transferrin endocytosis and trafficking through early endosomes. | ||||||||
| Note | For research use only |
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