Anti-Rabbit CACNA1C Recombinant Antibody (L57/23R) (TC588013)

Name: Anti-Rabbit CACNA1C Recombinant Antibody (L57/23R)
Brand: abinScience
SKU: TC588013
Price: 191 USD
Availability: InStock

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Overview

Catalog No.	TC588013
Species reactivity	Rabbit
Applications	IHC
Host species	Mouse
Isotype	IgG2a
Clone ID	L57/23R
Clonality	Monoclonal
Target	Target name:CACNA1C, CACH2, CACN2, CACNL1A1, CCHL1A1, Voltage-dependent L-type calcium channel subunit alpha-1C, Calcium channel L type alpha-1 polypeptide, Smooth muscle calcium channel blocker receptor, CACB-receptor, Voltage-gated calcium channel subunit alpha Cav1.2
Endotoxin level	Please contact with the lab for this information.
Purity	>95% as determined by SDS-PAGE.
Purification	Protein A/G purified from cell culture supernatant.
Accession	P15381
RRID	Anti-Rabbit CACNA1C Antibody (L57/23R) (abinScience Cat# TC588013, RRID:AB_3726996)
Form	Liquid
Storage buffer	0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Background	Voltage-dependent L-type calcium channel subunit alpha-1C (CACNA1C) is a ~242 kDa protein. Pore-forming, alpha-1C subunit of the voltage-gated calcium channel that gives rise to L-type calcium currents. Mediates influx of calcium ions into the cytoplasm, and thereby triggers calcium release from the sarcoplasm. Plays an important role in excitation-contraction coupling in the heart. Required for normal heart development and normal regulation of heart rhythm. Required for normal contraction of smooth muscle cells in blood vessels and in the intestine. 1. Cohen, RM. et al. (2005) American journal of physiology. Heart and circulatory physiology 288, H2363-74. PMID: 15615847 2. Yada, H. et al. (2007) Circulation research 101, 69-77. PMID: 17525370 3. Yang, L. et al. (2011) FASEB journal : official publication of the Federation of American Societies for Experimental Biology 25, 928-36. PMID: 21127204 4. Biel, M. et al. (1990) FEBS letters 269, 409-12. PMID: 2169433 5. Almagor, L. et al. (2012) The Journal of neuroscience : the official journal of the Society for Neuroscience 32, 7602-13. PMID: 22649239 6. Nakada, T. et al. (2012) The Biochemical journal 448, 221-31. PMID: 22928916 7. Gez, LS. et al. (2012) Biochemistry 51, 9658-66. PMID: 23145875 8. Mikami, A. et al. (1989) Nature 340, 230-3. PMID: 2474130 9. Campiglio, M. et al. (2018) Proceedings of the National Academy of Sciences of the United States of America 115, 1376-1381. PMID: 29363593 10. Yang, J. et al. (1993) Nature 366, 158-61. PMID: 8232554
Note	For research use only.

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SDS-PAGE

SDS-PAGE for Anti-Rabbit CACNA1C Antibody (L57/23R)

References

Datasheet

Anti-Rabbit CACNA1C Recombinant Antibody (L57/23R).pdf

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Anti-Rabbit CACNA1C Recombinant Antibody (L57/23R) (TC588013)

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