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Anti-Ranibizumab Polyclonal Antibody (AB941014)

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Overview
Catalog No.AB941014
Description
Anti-Ranibizumab Polyclonal Antibody (AB941014) is a rabbit polyclonal antibody detecting Ranibizumab in ELISA.
Highlights
  • ●Affinity Purified — Minimal background and high purity for reliable results.
Species reactivityGeneral
ApplicationsELISA
Host speciesRabbit
ClonalityPolyclonal
IsotypeIgG
Immunogen Ranibizumab
Target Rabbit polyclonal to Lucentis.
Specificity The product is specific for Ranibizumab. This antibody serves as an excellent positive control for Ranibizumab immunogenicity (ADA) assays.
Endotoxin level Please contact with the lab for this information.
Purity >90% as determined by SDS-PAGE.
Purification Purified by antigen affinity column.
Accession CAS: 347396-82-1
Form Liquid
Storage buffer 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Product Usage Information
Application Dilution
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Stability and Storage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Background

Ranibizumab with trade name Lucentis, is an FDA-approved drug for the treatment of patients with neovascular (Wet) age-related macular degeneration (AMD) and macular edema following retinal vein occlusion (RVO). It is a recombinant humanized IgG1 kappa isotype monoclonal antibody fragment. Ranibizumab binds to vascular endothelial growth factor A (VEGF-A) and blocks its activity. Antibodysystem Anti-Ranibizumab Antibody, pAb, Rabbit is produced from sera of a rabbit immunized with Ranibizumab.

Note For research use only.
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Datasheet
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Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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Anti-Ranibizumab Polyclonal Antibody

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