

| Catalog No. | RP768014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Description |
Anti-Rat Mbl1 Polyclonal Antibody (RP768014) is a rabbit polyclonal antibody detecting Mbl1 in ELISA, IHC, WB. Suitable for Rat.
Highlights
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| Species reactivity | Rat | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Host species | Rabbit | ||||||||
| Isotype | IgG | ||||||||
| Clonality | Polyclonal | ||||||||
| Immunogen | E. coli - derived recombinant Rat Mbl1 (Gly86-Ala238). | ||||||||
| Target | Mannose-binding protein A, MBP-A, Mannan-binding protein, Mbl1 | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Accession | P19999 | ||||||||
| Form | Liquid | ||||||||
| Storage buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| Product Usage Information |
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| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Background | Mannose-binding protein A (Mbl1) is a ~25 kDa protein. Calcium-dependent lectin. Plays a role in the innate immune response by binding mannose, fucose and N-acetylglucosamine moieties on different microorganisms and mediating activation of the lectin complement pathway. Binds to late apoptotic cells, as well as to apoptotic blebs and to necrotic cells, but not to early apoptotic cells, facilitating their uptake by macrophages. 1. Ng, KK. et al. (2002) The Journal of biological chemistry 277, 16088-95. PMID: 11850428 2. Weis, WI. et al. (1992) Nature 360, 127-34. PMID: 1436090 3. Ng, KK. et al. (1997) Biochemistry 36, 979-88. PMID: 9033386 4. Ikeda, K. et al. (1987) The Journal of biological chemistry 262, 7451-4. PMID: 3584121 | ||||||||
| Note | For research use only. |
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