Anti-Rat VEGFA Recombinant Antibody (SAA0447) (RB941207)

Name: Anti-Rat VEGFA Recombinant Antibody (SAA0447)
Brand: abinScience
SKU: RB941207
Price: 196 USD
Availability: InStock

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Overview

Catalog No.	RB941207
Species reactivity	Rat
Applications	ELISA, FCM
Host species	Mouse
Clonality	Monoclonal
Isotype	IgG2a, kappa
Clone ID	SAA0447
Target	L-VEGF, N-VEGF, VEGF, VEGFA, VPF, Vascular endothelial growth factor A, long form, Vascular permeability factor
Endotoxin level	< 10 EU/mg
Purity	>95% as determined by SDS-PAGE.
Purification	Protein A/G purified from cell culture supernatant.
Accession	P16612
Form	Liquid
Storage buffer	0.01M PBS pH 7.4. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Background	Vascular endothelial growth factor A (VEGFA) is a ~25 kDa protein. Growth factor active in angiogenesis, vasculogenesis and endothelial cell growth. Induces endothelial cell proliferation, promotes cell migration, inhibits apoptosis and induces permeabilization of blood vessels. Binds to the FLT1/VEGFR1 and KDR/VEGFR2 receptors, heparan sulfate and heparin. May play a role in increasing vascular permeability during lactation, when increased transport of molecules from the blood is required for efficient milk protein synthesis. Binding to NRP1 receptor initiates a signaling pathway needed for motor neuron axon guidance and cell body migration, including for the caudal migration of facial motor neurons from rhombomere 4 to rhombomere 6 during embryonic development. VEGFA is the therapeutic target of bevacizumab (Avastin).
Note	For research use only.

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Datasheet

Anti-Rat VEGFA Recombinant Antibody (SAA0447).pdf

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Anti-Rat VEGFA Recombinant Antibody (SAA0447) (RB941207)

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Datasheet

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