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Anti-Rat VEGFA Recombinant Antibody (SAA0447) (RB941207)

Anti-Rat VEGFA Recombinant Antibody (SAA0447)
Anti-Rat VEGFA Recombinant Antibody (SAA0447)
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Overview
Catalog No.RB941207
Species reactivityRat
ApplicationsELISA, FCM
Host speciesMouse
IsotypeIgG2a, kappa
Clone IDSAA0447
Clonality Monoclonal
Target Vascular endothelial growth factor A, VPF, VEGFA, VEGF, Vascular permeability factor, VEGF-A
Endotoxin level Please contact with the lab for this information.
Purity >95% as determined by SDS-PAGE.
Purification Protein A/G purified from cell culture supernatant.
Accession P16612
Form Liquid
Storage buffer 0.01M PBS, pH 7.4, 0.09% Sodium azide.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Stability and Storage Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Background

Vascular endothelial growth factor A (VEGFA) is a ~25 kDa protein. Growth factor active in angiogenesis, vasculogenesis and endothelial cell growth. Induces endothelial cell proliferation, promotes cell migration, inhibits apoptosis and induces permeabilization of blood vessels. Binds to the FLT1/VEGFR1 and KDR/VEGFR2 receptors, heparan sulfate and heparin. May play a role in increasing vascular permeability during lactation, when increased transport of molecules from the blood is required for efficient milk protein synthesis. Binding to NRP1 receptor initiates a signaling pathway needed for motor neuron axon guidance and cell body migration, including for the caudal migration of facial motor neurons from rhombomere 4 to rhombomere 6 during embryonic development. VEGFA is the therapeutic target of bevacizumab (Avastin).

Note For research use only.
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  • Anti-Rat VEGFA Recombinant Antibody (SAA0447)

    SDS-PAGE

    SDS-PAGE for Anti-Rat VEGFA Antibody (SAA0447)

References
Formula
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Formula
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