

| Catalog No. | HC507014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Description |
Anti-REG3A Polyclonal Antibody (HC507014) is a rabbit polyclonal antibody detecting REG3A in ELISA, IHC, WB. Suitable for Human.
Highlights
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| Species reactivity | Human | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Host species | Rabbit | ||||||||
| Isotype | IgG | ||||||||
| Clonality | Polyclonal | ||||||||
| Immunogen | E. coli - derived recombinant Human REG3A (Cys40-Asn164). | ||||||||
| Target | Regenerating islet-derived protein 3-alpha, PAP1, Regenerating islet-derived protein III-alpha, Hepatointestinal pancreatic protein, REG-3-alpha, HIP, REG3A, Pancreatitis-associated protein 1, Human proislet peptide, PAP, HIP/PAP, Reg III-alpha | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Accession | Q06141 | ||||||||
| Form | Liquid | ||||||||
| Storage buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| Product Usage Information |
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| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Background | Regenerating islet-derived protein 3-alpha (REG3A) is a ~19 kDa protein. Bactericidal C-type lectin which acts exclusively against Gram-positive bacteria and mediates bacterial killing by binding to surface-exposed carbohydrate moieties of peptidoglycan. Binds membrane phospholipids and kills bacteria by forming a hexameric membrane-permeabilizing oligomeric pore. 1. Cash, HL. et al. (2006) Science (New York, N.Y.) 313, 1126-30. PMID: 16931762 2. Mukherjee, S. et al. (2014) Nature 505, 103-7. PMID: 24256734 | ||||||||
| Note | For research use only. |
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