

| Catalog No. | HB428014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Description |
Anti-RGS1 Polyclonal Antibody (HB428014) is a rabbit polyclonal antibody detecting Regulator of G-protein signaling 1; RGS1; B-cell activation protein BL34; Early response protein 1R20; RGS1; 1R20; BL34; IER1 in ELISA, IHC, WB. Suitable for Human, Horse, Rat, and Mouse.
Highlights
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| Species reactivity | Human | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Host species | Rabbit | ||||||||
| Clonality | Polyclonal | ||||||||
| Isotype | IgG | ||||||||
| Immunogen | E. coli - derived recombinant human RGS1 (Ser75-Lys209). | ||||||||
| Target | Regulator of G-protein signaling 1; RGS1; B-cell activation protein BL34; Early response protein 1R20; RGS1; 1R20; BL34; IER1 | ||||||||
| Endotoxin level | Please contact with the lab for this information. | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Accession | Q08116, Q6RG78, P97844, Q9JL25 | ||||||||
| Form | Liquid | ||||||||
| Storage buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| Product Usage Information |
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| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Background | Regulator of G-protein signaling 1 (RGS1) is a ~23 kDa protein. Regulates G protein-coupled receptor signaling cascades, including signaling downstream of the N-formylpeptide chemoattractant receptors and leukotriene receptors. Inhibits B cell chemotaxis toward CXCL12. Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. 1. Denecke, B. et al. (1999) The Journal of biological chemistry 274, 26860-8. PMID: 10480894 2. Soundararajan, M. et al. (2008) Proceedings of the National Academy of Sciences of the United States of America 105, 6457-62. PMID: 18434541 | ||||||||
| Note | For research use only |
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