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Anti-RGS8 Polyclonal Antibody (HB320014)

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Overview
Catalog No.HB320014
Description
Anti-RGS8 Polyclonal Antibody (HB320014) is a rabbit polyclonal antibody detecting Regulator of G-protein signaling 8; RGS8; RGS8 in ELISA, IHC, WB. Suitable for Human, Rat, and Mouse.
Highlights
  • ●Affinity Purified — Minimal background and high purity for reliable results.
  • ●Multi-Application — Validated across multiple applications.
  • ●Multi-Species — Cross-reactive for translational research.
Species reactivityHuman, Mouse, Rat
ApplicationsELISA, IHC, WB
Host speciesRabbit
ClonalityPolyclonal
IsotypeIgG
Immunogen E. coli - derived recombinant human RGS8 (Asp29-Ser180).
Target Regulator of G-protein signaling 8; RGS8; RGS8
Endotoxin level Please contact with the lab for this information.
Purification Purified by antigen affinity column.
Accession P57771, P49804, Q8BXT1
Form Liquid
Storage buffer 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Product Usage Information
Application Dilution
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Stability and Storage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Background

Regulator of G-protein signaling 8 (RGS8) is a ~20 kDa protein. Regulates G protein-coupled receptor signaling cascades, including signaling via muscarinic acetylcholine receptor CHRM2 and dopamine receptor DRD2. Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP-bound form. Modulates the activity of potassium channels that are activated in response to DRD2 and CHRM2 signaling.

1. Soundararajan, M. et al. (2008) Proceedings of the National Academy of Sciences of the United States of America 105, 6457-62. PMID: 18434541
Note For research use only
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Datasheet
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Formula
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Working Solution
C₂ (Working Conc.)
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Anti-RGS8 Polyclonal Antibody

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