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Anti-RTN4R/NgR1/Nogor Recombinant Antibody (M5) (HP096013)

Anti-RTN4R/NgR1/Nogor Recombinant Antibody (M5)
Anti-RTN4R/NgR1/Nogor Recombinant Antibody (M5)
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Overview
Catalog No.HP096013
Species reactivityHuman
ApplicationsELISA, FCM, IF, IP, SPR, WB
Host speciesHuman
IsotypeIgG1
Clone IDM5
Clonality Monoclonal
Target NgR, Nogo receptor, Reticulon-4 receptor, RTN4R, Nogo-66 receptor, NOGOR
Endotoxin level Please contact with the lab for this information.
Purity >95% as determined by SDS-PAGE.
Purification Protein A/G purified from cell culture supernatant.
Accession Q9BZR6
RRID

Anti-RTN4R/NgR1/Nogor Antibody (M5) (abinScience Cat# HP096013, RRID:AB_3729079)
_x005F_x000D_

Form Liquid
Storage buffer 0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information
Application Dilution
ELISA 1:2000-1:20000
WB 1:500-1:2000
Stability and Storage Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Background

Reticulon-4 receptor (RTN4R/NgR1) is a ~50 kDa protein. Receptor for RTN4, OMG and MAG. Functions as a receptor for the sialylated gangliosides GT1b and GM1. Besides, functions as a receptor for chondroitin sulfate proteoglycans. Can also bind heparin. Intracellular signaling cascades are triggered via the coreceptor NGFR.

1. GrandPré, T. et al. (2002) Nature 417, 547-51. PMID: 12037567
2. Wang, KC. et al. (2002) Nature 417, 941-4. PMID: 12068310
3. Liu, BP. et al. (2002) Science (New York, N.Y.) 297, 1190-3. PMID: 12089450
4. Wong, ST. et al. (2002) Nature neuroscience 5, 1302-8. PMID: 12426574
5. Barton, WA. et al. (2003) The EMBO journal 22, 3291-302. PMID: 12839991
6. Teusch, N. et al. (2006) Assay and drug development technologies 4, 133-41. PMID: 16712417
7. Williams, G. et al. (2008) The Journal of biological chemistry 283, 16641-52. PMID: 18411262
8. Budel, S. et al. (2008) The Journal of neuroscience : the official journal of the Society for Neuroscience 28, 13161-72. PMID: 19052207
9. Wills, ZP. et al. (2012) Neuron 73, 466-81. PMID: 22325200
Note For research use only.
Images
  • Anti-RTN4R/NgR1/Nogor Recombinant Antibody (M5)

    SDS-PAGE

    SDS-PAGE for Anti-RTN4R/NgR1/Nogor Antibody (M5)

References
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
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