

| Catalog No. | VK676074 | ||||
|---|---|---|---|---|---|
| Description |
Anti-RV-A NSP2 Polyclonal Antibody (VK676074) is a rabbit polyclonal antibody detecting NSP2 in ELISA, IHC, WB. Suitable for Rotavirus A.
Highlights
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| Species reactivity | Rotavirus A (RV-A) | ||||
| Applications | ELISA, IHC, WB | ||||
| Host species | Rabbit | ||||
| Clonality | Polyclonal | ||||
| Isotype | IgG | ||||
| Immunogen | E. coli - derived recombinant RV-A NSP2 (Met1-Val317). | ||||
| Target | viroplasm RNA-binding protein NSP2, NSP2 | ||||
| Endotoxin level | Please contact with the lab for this information. | ||||
| Purification | Purified by antigen affinity column. | ||||
| Accession | Q03243, B2BRG3, B3SRR4, B3SRX8, P09366, A4ZCW3, Q03245, Q9QNA8, B3SRX0, B3SRV4, B3SRS2, A2T3M2, D5LJN4, Q3ZK62, A2T3P0, P03538, A3DSK8, B3SRQ6, Q03242, P03537 | ||||
| Form | Liquid | ||||
| Storage buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| Product Usage Information |
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| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||
| Background | Non-structural protein 2 (NSP2) is a ~36 kDa protein. Participates in replication and packaging of the viral genome. Plays a crucial role, together with NSP5, in the formation of virus factories (viroplasms), which are large inclusions in the host cytoplasm where replication intermediates are assembled and viral RNA replication takes place. Displays ssRNA binding, NTPase, RNA triphosphatase (RTPase) and ATP-independent helix-unwinding activities. The unwinding activity may prepare and organize plus-strand RNAs for packaging and replication by removing interfering secondary structures. The RTPase activity plays a role in the removal of the gamma-phosphate from the rotavirus RNA minus strands of dsRNA genome segments. | ||||
| Note | For research use only |
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