Anti-SCO2 Polyclonal Antibody (HT314014)

Name: Anti-SCO2 Polyclonal Antibody
Brand: abinScience
SKU: HT314014
Price: 168 USD
Availability: InStock

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Datasheet
SDS

Overview

Catalog No.

HT314014

Description

Anti-SCO2 Polyclonal Antibody (HT314014) is a rabbit polyclonal antibody detecting SCO2 in ELISA, IHC, WB. Suitable for Bovine, Human, and Mouse.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

Species reactivity

Human

Applications

ELISA, IHC, WB

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human SCO2 (Gly42-Ser266).

Target

Protein SCO2 homolog, mitochondrial, SCO2

Endotoxin level

Please contact with the lab for this information.

Purification

Purified by antigen affinity column.

Accession

O43819

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Background

Cytochrome c oxidase assembly factor SCO2 is a ~29 kDa protein. Copper metallochaperone essential for the synthesis and maturation of cytochrome c oxidase subunit II (MT-CO2/COX2); together with SCO1, facilitates the incorporation of copper into the Cu(A) site of MT-CO2/COX2. Could also act as a thiol-disulfide oxidoreductase to regulate the redox state of the cysteines in SCO1 during maturation of MT-CO2/COX2.

1. Leary, SC. et al. (2004) Human molecular genetics 13, 1839-48. PMID: 15229189

2. Leary, SC. et al. (2007) Cell metabolism 5, 9-20. PMID: 17189203

3. Leary, SC. et al. (2009) Human molecular genetics 18, 2230-40. PMID: 19336478

4. Nývltová, E. et al. (2022) Nature communications 13, 3615. PMID: 35750769

Note

For research use only.

Images

References

Datasheet

Anti-SCO2 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

Assay Kits

Anti-SCO2 Polyclonal Antibody (HT314014)

Overview

Images

References

Datasheet

SDS

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