Anti-SEC24A Polyclonal Antibody (HB391014)

Name: Anti-SEC24A Polyclonal Antibody
Brand: abinScience
SKU: HB391014
Price: 168 USD
Availability: InStock

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Overview
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References
Datasheet
SDS

Overview

Catalog No.

HB391014

Description

Anti-SEC24A Polyclonal Antibody (HB391014) is a rabbit polyclonal antibody detecting Protein transport protein Sec24A; SEC24-related protein A; SEC24A in ELISA, IHC, WB. Suitable for Human, Bovine, and Mouse.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

Species reactivity

Human, Mouse

Applications

ELISA, IHC, WB

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Immunogen

E. coli - derived recombinant human SEC24A (His943-Lys1093).

Target

Protein transport protein Sec24A; SEC24-related protein A; SEC24A

Endotoxin level

Please contact with the lab for this information.

Purification

Purified by antigen affinity column.

Accession

O95486, A6QNT8, Q3U2P1

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Background

Protein transport protein Sec24A is a ~119 kDa protein. Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules for their transport to the Golgi complex. Plays a central role in cargo selection within the COPII complex and together with SEC24B may have a different specificity compared to SEC24C and SEC24D. May package preferentially cargos with cytoplasmic DxE or LxxLE motifs and may also recognize conformational epitopes.

1. Mancias, JD. et al. (2007) Molecular cell 26, 403-14. PMID: 17499046

2. Mancias, JD. et al. (2008) The EMBO journal 27, 2918-28. PMID: 18843296

3. Bonnon, C. et al. (2010) Journal of cell science 123, 1705-15. PMID: 20427317

Note

For research use only

Images

References

Datasheet

Anti-SEC24A Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

Assay Kits

Anti-SEC24A Polyclonal Antibody (HB391014)

Overview

Images

References

Datasheet

SDS