

| Catalog No. | HF673014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Species reactivity | Human | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Host species | Rabbit | ||||||||
| Isotype | IgG | ||||||||
| Clonality | Polyclonal | ||||||||
| Immunogen | E. coli - derived recombinant Human SERPINC1 (His33-Lys464). | ||||||||
| Target | Serpin C1, ATIII, AT3, SERPINC1, Antithrombin-III | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Accession | P01008 | ||||||||
| Form | Liquid | ||||||||
| Storage buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| Product Usage Information |
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| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Background | Antithrombin-III (SERPINC1) is a ~52 kDa protein. Most important serine protease inhibitor in plasma that regulates the blood coagulation cascade. AT-III inhibits thrombin, matriptase-3/TMPRSS7, as well as factors IXa, Xa and XIa. Its inhibitory activity is greatly enhanced in the presence of heparin. 1. Corral, J. et al. (2004) Journal of thrombosis and haemostasis : JTH 2, 931-9. PMID: 15140129 2. Szabo, R. et al. (2005) The Biochemical journal 390, 231-42. PMID: 15853774 | ||||||||
| Note | For research use only. |
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