

| Catalog No. | HY496014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Description |
Anti-SERPING1 Polyclonal Antibody (HY496014) is a rabbit polyclonal antibody detecting SERPING1 in ELISA, IHC, WB. Suitable for Human and Rat.
Highlights
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| Species reactivity | Human | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Host species | Rabbit | ||||||||
| Isotype | IgG | ||||||||
| Clonality | Polyclonal | ||||||||
| Immunogen | E. coli - derived recombinant Human SERPING1 (Pro399-Ala500). | ||||||||
| Target | Serpin G1, SERPING1, C1Inh, C1 esterase inhibitor, Plasma protease C1 inhibitor, C1IN, C1 Inh, C1NH, C1-inhibiting factor | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Accession | P05155 | ||||||||
| Form | Liquid | ||||||||
| Storage buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| Product Usage Information |
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| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Background | Plasma protease C1 inhibitor (SERPING1) is a ~55 kDa protein. Serine protease inhibitor, which acrs as a regulator of the classical complement pathway. Forms a proteolytically inactive stoichiometric complex with the C1r or C1s proteases. May also regulate blood coagulation, fibrinolysis and the generation of kinins. Very efficient inhibitor of FXIIa. Inhibits chymotrypsin and kallikrein. 1. Matsushita, M. et al. (2000) Journal of immunology (Baltimore, Md. : 1950) 165, 2637-42. PMID: 10946292 2. Rossi, V. et al. (2001) The Journal of biological chemistry 276, 40880-7. PMID: 11527969 3. Davis, AE. et al. (1986) Proceedings of the National Academy of Sciences of the United States of America 83, 3161-5. PMID: 3458172 4. Harrison, RA. (1983) Biochemistry 22, 5001-7. PMID: 6416294 5. Aulak, KS. et al. (1993) Protein science : a publication of the Protein Society 2, 727-32. PMID: 8495195 | ||||||||
| Note | For research use only. |

Western blot analysis was performed using anti-SERPING1 polyclonal antibody at 1ug/mL on recombinant SERPING1 (Catalog No. HY496012).
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