Anti-SERPINI1 Polyclonal Antibody (MC075014)

Name: Anti-SERPINI1 Polyclonal Antibody
Brand: abinScience
SKU: MC075014
Price: 96 USD
Availability: InStock

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Overview
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References
Datasheet
SDS

Overview

Catalog No.

MC075014

Description

Anti-SERPINI1 Polyclonal Antibody (MC075014) is a rabbit polyclonal antibody detecting Neuroserpin; Peptidase inhibitor 12; PI-12; Serine protease inhibitor 17; Serpin I1; Serpini1; Pi12; Spi17 in ELISA, IHC, WB. Suitable for Mouse, Human, and Rat.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

Species reactivity

Mouse, Rat

Applications

ELISA, IHC, WB

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Immunogen

E. coli - derived recombinant mouse SERPINI1 (Thr17-Leu410).

Target

Neuroserpin; Peptidase inhibitor 12; PI-12; Serine protease inhibitor 17; Serpin I1; Serpini1; Pi12; Spi17

Endotoxin level

Please contact with the lab for this information.

Purification

Purified by antigen affinity column.

Accession

Q99574, O35684, Q9JLD2

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Background

Neuroserpin (SERPINI1) is a ~46 kDa protein. Serine protease inhibitor that inhibits plasminogen activators and plasmin but not thrombin. May be involved in the formation or reorganization of synaptic connections as well as for synaptic plasticity in the adult nervous system. May protect neurons from cell damage by tissue-type plasminogen activator (Probable).

1. Belorgey, D. et al. (2002) The Journal of biological chemistry 277, 17367-73. PMID: 11880376

2. Ricagno, S. et al. (2009) Journal of molecular biology 388, 109-21. PMID: 19265707

3. Takehara, S. et al. (2009) Journal of molecular biology 388, 11-20. PMID: 19285087

4. Noto, R. et al. (2015) Scientific reports 5, 13666. PMID: 26329378

5. Osterwalder, T. et al. (1998) The Journal of biological chemistry 273, 2312-21. PMID: 9442076

Note

For research use only

Images

Western blot

Western blot analysis was performed using anti-SERPINI1 polyclonal antibody at 1ug/mL on various samples.
Lane 1: K562 cell lysate

References

Datasheet

Anti-SERPINI1 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

Assay Kits

Anti-SERPINI1 Polyclonal Antibody (MC075014)

Overview

Images

References

Datasheet

SDS

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