Anti-SLC1A4 Polyclonal Antibody (HA640014)

Name: Anti-SLC1A4 Polyclonal Antibody
Brand: abinScience
SKU: HA640014
Price: 168 USD
Availability: InStock

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Overview
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References
Datasheet
SDS

Overview

Catalog No.

HA640014

Description

Anti-SLC1A4 Polyclonal Antibody (HA640014) is a rabbit polyclonal antibody detecting Neutral amino acid transporter A; Alanine/serine/cysteine/threonine transporter 1; ASCT-1; Solute carrier family 1 member 4; SLC1A4; ASCT1; SATT in ELISA, IHC, WB. Suitable for Human and Bovine.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

Species reactivity

Human

Applications

ELISA, IHC, WB

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Immunogen

E. coli - derived recombinant human SLC1A4 (Lys140-Thr216).

Target

Neutral amino acid transporter A; Alanine/serine/cysteine/threonine transporter 1; ASCT-1; Solute carrier family 1 member 4; SLC1A4; ASCT1; SATT

Endotoxin level

Please contact with the lab for this information.

Purification

Purified by antigen affinity column.

Accession

P43007, A2VDL4

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Background

Neutral amino acid transporter A (SLC1A4) is a ~55 kDa protein. Sodium-coupled antiporter of neutral amino acids. In a tri-substrate transport cycle, exchanges neutral amino acids between the extracellular and intracellular compartments, coupled to the inward cotransport of at least one sodium ion. Exchanges neutral amino acids such as L- and D-serine, L-threonine, L-asparagine and L-alanine in a bidirectional way. Involved in homeostasis of D-serine, a coagonist of synaptic NMDA receptors. In astrocytes at excitatory synapses, mediates electrogenic D-serine influx coupled to L-serine efflux and L-serine shuttling to neurons for de novo D-serine synthesis.

1. Scopelliti, AJ. et al. (2014) The Journal of biological chemistry 289, 17468-79. PMID: 24808181

2. Foster, AC. et al. (2016) PloS one 11, e0156551. PMID: 27272177

3. Stehantsev, P. et al. (2021) Computational and structural biotechnology journal 19, 5246-5254. PMID: 34630942

4. Zerangue, N. et al. (1996) The Journal of biological chemistry 271, 27991-4. PMID: 8910405

5. Pinilla-Tenas, J. et al. (2003) The Journal of membrane biology 195, 27-32. PMID: 14502423

6. Damseh, N. et al. (2015) Journal of medical genetics 52, 541-7. PMID: 26041762

7. Arriza, JL. et al. (1993) The Journal of biological chemistry 268, 15329-32. PMID: 8101838

8. Shafqat, S. et al. (1993) The Journal of biological chemistry 268, 15351-5. PMID: 8340364

Note

For research use only

Images

References

Datasheet

Anti-SLC1A4 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

Assay Kits

Anti-SLC1A4 Polyclonal Antibody (HA640014)

Overview

Images

References

Datasheet

SDS