Anti-SNV Glycoprotein Gc Polyclonal Antibody (VK019014)

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Overview

Catalog No.

VK019014

Description

Anti-SNV Glycoprotein Gc Polyclonal Antibody (VK019014) is a rabbit polyclonal antibody detecting Glycoprotein C in WB, IHC, ELISA. Suitable for Sin Nombre Virus, CASV-2 Hantavirus, Lechiguanas virus, Blue River virus, and Necocli virus.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

Species reactivity

Sin Nombre Virus, Limestone Canyon virus, CASV-2 Hantavirus, Orthohantavirus andesense, Lechiguanas virus, Blue River virus, Convict Creek 107 virus, Orthohantavirus bayoui, Necocli virus, Catacamas virus, Orthohantavirus montanoense, New York virus, Monongahela hantavirus

Applications

WB,IHC,ELISA

Host species

Rabbit

Isotype

IgG

Species

Sin Nombre orthohantavirus (SNV)

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant SNV Glycoprotein (Asp653-Glu1099).

Target

Envelopment polyprotein, Glycoprotein C, Gc, Glycoprotein G2, GP

Endotoxin level

Please contact with the lab for this information.

Purity

>90% as determined by SDS-PAGE.

Purification

Purified by antigen affinity column.

Accession

Q89905, Q83887, Q9E006

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Background

Envelopment polyprotein (Gc) is a ~125 kDa protein. Forms homotetramers with glycoprotein C at the surface of the virion. Attaches the virion to host cell receptors including integrin ITGAV/ITGB3 (Probable). This attachment induces virion internalization predominantly through clathrin-dependent endocytosis. Mediates the assembly and budding of infectious virus particles through its interaction with the nucleocapsid protein and the viral genome. May dysregulate normal immune and endothelial cell responses through an ITAM motif.

Note

For research use only.

Images

References

Datasheet

Anti-SNV Glycoprotein Gc Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

Assay Kits

Anti-SNV Glycoprotein Gc Polyclonal Antibody (VK019014)

Overview

Images

References

Datasheet

SDS

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